Davidson model and system biology model

Project Leader: Yawen Zou

Eric H. Davidson has generated a complex regulatory network of development in sea urchin empirical experiments and computational tools. System biology is a field that emphasize on complexity, large data, and computational tools too. Furthermore, both Davidson and system biologists are interested in a same set of biological problems and concepts: modularity, cis-regulatory elements, to name a few. Of course, there are also discrepancies in the two research areas: Davidson is mainly interested in gene network, whereas system biologists also look at metabolic and protein networks. My interest is in how Davidson's gene regulatory network research overlaps with what system biologists are doing. My goal is to analyze selected literature of the two areas, generate two models of the network structure of system biology and Davidson's research, and make a quantitative comparison of these two different fields of research.